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韩兰芝

文章来源:研究生工作处       

韩兰芝,女,1976年6月出生,山东郓城县人,博士,研究员,硕士生导师。

1999年获青岛农业大学植物保护专业学士学位,2004年获南京农业大学农业昆虫与害虫防治专业博士学位,2007年6月从亚搏app生物安全专业博士后流动站出站并留所工作至今。2012年11月-2013年12月在美国田纳西大学昆虫学专业进行访学合作研究。

韩兰芝研究员长期从事转基因抗虫作物靶标害虫的抗性风险评及抗性治理研究,主要研究内容包括:靶标害虫对转基因抗虫作物的抗性风险评价、抗性演化机制、抗性风险管理及昆虫肠道微生物与宿主和Bt杀虫蛋白的协同进化机制等。先后主持国家自然科学基金项目(30800723和31572336)、转基因生物新品种培育重大专项重点课题(2009ZX08011-007B)和子课题“RNAi转基因植物环境安全评价技术(2018ZX0801101B-002)”等。作为主要科研骨干承担转基因生物新品种培育重大专项课题(2016ZX08011-001, 2014ZX08011-001, 2013ZX08011-001, 2011ZX08011-001, 2008ZX08011-001)、农业部财政专项-农产品质量安全项目等课题。以第一/通讯作者在Current Opinion in Insect Science, Journal of Agricultural and Food Chemistry, Applied Environmental and Microbiology, Pest Management Science, Journal of Invertebrate Pathology等国际期刊和国内核心期刊共发表学术论文50余篇,以第一作者获得授权的国家发明专利4项,参编著作4部。

联系方式:

Tel: 010-62819620; Email: hanlanzhi@caas.cn

作为第一/通讯作者(*)发表的代表性论文:

  1. Chen JJ, Wang HH, Yang XX, Chen G, Du LX, Chen H, Li YH, Peng YF, Han LZ*. 2021. Consumption of miRNA-mediated insect-resistant transgenic rice pollen does not harm Apis mellifera adults. Journal of Agricultural and Food Chemistry, 69, 14: 4234-4242.
  2. Wen N, Chen JJ, Chen G, Du LX, Chen H, Li YH, Peng YF, Yang XW*, Han LZ*. 2021. The overexpression of insect endogenous microRNA in transgenic rice inhibits the pupation of Chilo suppressalis and Cnaphalocrocis medinalis. Pest Management Science, DOI 10.1002/ps.6422 
  3. Chen G, Wang YH, Liu YM, Chen FJ, Han LZ*. 2020. Differences in midgut transcriptomes between resistant and susceptible strains of Chilo suppressalis to Cry1C toxin. BMC Genomics, 21: 634-653.
  4. Zhang C, Luo J, Chen G, Han LZ*, Peng YF. 2019. A new method to obtain isofemale lines for monitoring Chilo suppressalis resistance to Bt toxin. Journal of Invertebrate Pathology, 163, 8-10.
  5. Du LX, Chen G, Han LZ*, Peng YF. 2019. Cadherin CsCad plays differential functional roles in Cry1Ab and Cry1C intoxication in Chilo suppressalis. Scientific Report, 9: 8507.
  6. Zhou YC, Jia BT, Han LZ*, Peng YF. 2019. A morphological and functional characterization of isolated stem cells from the midgut of Chilo suppressalis larvae. Journal of Asia-Pacific Entomology, 22(3): 982-989.
  7. Tang H, Chen G, Chen FJ, Han LZ*, Peng YF. 2018. Development and relative fitness of Cry1C resistance in Chilo suppressalis. Pest Manage Science, 74:590-597.
  8. Wang XY, Du LX, Liu CX, Gong L, Han LZ*, Peng YF. 2017. RNAi in the striped stem borer, Chilo suppressalis, establishes a functional role for aminopeptidase N in Cry1Ab intoxication. Journal of Invertebrate Pathology, 143: 1-10.
  9. Han LZ*, Jiang XF, Peng YF. 2016. Potential resistance management for the sustainable use of insect-resistant genetically modified corn and rice in China. Current Opinion in Insect Science. 15:139-143.
  10. Li B, Xu YY, Han C, Han LZ*, Hou ML, Peng YF. 2015. Chilo suppressalis and Sesamia inferens display different susceptibility responses to Cry1A insecticidal proteins. Pest Management Science, 71: 1433-1440.
  11. Liu YD, Han LZ, Hou ML. 2015. Loss of Genetic variation in laboratory colonies of Chilo suppressalis (Lepidoptera: Crambidae) revealed by mitochondrial and microsatellite DNA markers. Environal Entomology, 44(1): 73-80.
  12. Gong L, Wang HD, Qi JW, Han LZ, Hu MY, Jurat-Fuentes. 2015. Homologs to Cry toxin receptor genes in a de novo transcriptome and their altered expression in resistant Spodoptera litura larvae. Journal of Invertebrate Pathology, 129, 1-6.
  13. Han LZ*, Han C, Jurat-Fuentes JL, Hou ML, Peng YF. 2014. Binding site concentration explains the differential susceptibility of Chilo suppressalis and Sesamia inferens to cry1A-producing rice. Applied and Environmental Microbiology, 80 (16): 5134-5140.
  14. Wang YN, Ke KQ, Li YH, Han LZ, Liu YM, Hua HX, Peng YF, 2014. Comparison of three transgenic Bt rice lines for insecticidal protein expression and resistance against a target pest, Chilo suppressalis (Lepidoptera: Crambidae). Insect Science, 11(1):78-87
  15. Wang YN, Zhang L, Li YH, Han LZ, Liu YM, Zhu Z, Wang F, Peng YF, 2014. Expression of Cry1Ab protein in a marker-free transgenic Bt rice line and its efficacy in controlling a target pest, Chilo suppressalis (Lepidoptera: Crambidae). Environmental Entomology, 43(2): 528-536.
  16. Li YH, Hu L, Romeis J, Wang YN, Han LZ, Chen XP, Peng YF. 2014. Use of an artificial diet system to study the toxicity of gut-active insecticidal compounds on larvae of the green lacewing Chrysoperla sinica. Biological Control, 69: 45-51.
  17. Han LZ, Li SB, Peng YF, Hou ML. 2012. New artificial diet for continuous rearing of Chilo suppressalis. Ann. Entomol. Soc. Am. 2012, 105(2): 253-258.
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